AI-Driven Business Process Mining for Healthcare: Automated Discovery and Optimization of Clinical and Administrative Workflows

Cornelia Ifeoma Ejoh *

University of the District of Columbia, 4200 Connecticut Ave NW, Washington, DC 20008, United States of America.

Timilehin Emmanuel Odeyinka

Nexford University - 1015 15th Street NW, Suite 631, Washington, DC 20005, United States of America.

Williams Onwu Nduka

Iowa State University, 2433 Union Dr, Ames, IA 50011, United States of America.

Valerie Ojinika Ejiofor

University of Tampa, 401 W Kennedy Blvd, Tampa, FL 33606, United States of America.

Onyii Henry

University of the District of Columbia, 4200 Connecticut Ave NW, Washington, DC 20008, United States of America.

*Author to whom correspondence should be addressed.


Abstract

Healthcare systems globally face persistent inefficiencies in clinical and administrative workflows due to complex, variable processes and limited visibility into real executions. This study developed an AI-enabled process mining framework designed for the automated discovery and improvement of these workflows through remote analysis of publicly accessible event logs. Using the Sepsis Cases - Event Log.xes as the primary dataset, the study applied AI-assisted discovery techniques including Heuristics Miner, Fuzzy Miner, and trace clustering to model clinical pathways and administrative activities. Conformance checking via optimal alignments assessed adherence to expected guidelines, highlighting deviations and bottlenecks. Predictive optimization was achieved using a Long Short-Term Memory (LSTM) neural network for next-activity forecasting and bottleneck detection, producing simulated throughput time reductions of approximately 18%. Performance metrics indicated moderate but informative conformance results: fitness of 0.609, precision of 0.443, composite F1-score of 0.64, and an AUC-ROC of 0.931 for predictive monitoring. The framework effectively enabled remote, reproducible analysis without direct data access, providing a practical blueprint for data-driven workflow improvement in resource-constrained environments. Despite limitations involving dataset specificity and noise sensitivity, the approach advances process mining applications in healthcare by integrating artificial intelligence for actionable insights. Future work should emphasize multi-dataset validation, explainability, and real-time deployment to further strengthen scalability and clinical decision support impact.

Keywords: Process mining, artificial intelligence, healthcare workflows, event logs, workflow optimization


How to Cite

Ejoh, Cornelia Ifeoma, Timilehin Emmanuel Odeyinka, Williams Onwu Nduka, Valerie Ojinika Ejiofor, and Onyii Henry. 2026. “AI-Driven Business Process Mining for Healthcare: Automated Discovery and Optimization of Clinical and Administrative Workflows”. Journal of Engineering Research and Reports 28 (3):102-17. https://doi.org/10.9734/jerr/2026/v28i31824.

Downloads

Download data is not yet available.